Formed in the axilla by the union of the lateral root from the lateral cord and the medial root from the medial cord of the brachial plexus.
It runs distally in the arm, initially on the lateral side of the brachial arteryuntil it reaches the middle of the arm, where it crosses from lateral to medial and lies over the brachialis.
Then descends to the cubital fossa, where it lies deep to the bicipital aponeurosis and median cubital vein and, medial to the brachial artery.
The median nerve does not give rise to any branches in the arm but supplies articular branches to the elbow joint.
Enters the forearm between the two heads of pronator teres where it gives rise to the anterior interosseous nerve.
Runs deep to flexor digitorum superficialis (FDS) until just proximal to the wrist where it becomes superficial to this tendon.
The median nerve passes through the wrist in the carpal tunnel entering between palmaris longus and flexor carpi radialis, superficial to flexor digitorum superficialis.
Palmar cutaneous nerve arises approximately 5 cm proximal to the distal wrist crease and runs over the flexor retinaculum to supply cutaneous innervation to the skin over the thenar eminence.
The origin of the recurrent motor branch is variable. It usually arises just distal to the flexor retinaculum.
The median nerve gives off the:
The superficial layer of forearm flexor muscles of the forearm are innervated directly by the median nerve:
The anterior interosseous nerve is a motor branch of the median nerve. It arises between the two heads of pronator teres and runs on the anterior surface of the interosseous membrane.
Note: The posterior interosseous nerve is a branch of the radial nerve. It passes between the two heads of supinator to enter the posterior compartment of the forearm. It innervates most of the extensors of the wrist and digits.
"The deep layer of forearm flexors are innervated by the anterior interosseous nerve:
The recurrent motor branch of the median nerve is usually arises just distal to or within the carpal tunnel and then hooks back to supply the thenar muscles. However, it can also exit through or superficial to the flexor retinaculum and is therefore at risk of injury during carpal tunnel decompression.
The ulnar nerve is the motor supply to all the intrinsic muscles of the hand except ‘LOAF’ which are supplied by the motor recurrent branch of the median
nerve:
Lateral (radial) two lumbricals
Opponens pollicis (OP)
Abductor pollicis brevis (APB)
Flexor pollicis brevis (FPB) (superficial head)
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